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Discover DAXXIFY

The Peptide-Powered Frown Line Treatment

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Why Choose DAXXIFY?


DAXXIFY may last up to twice as long as conventional frown line treatments for some.*


The only long-lasting frown line treatment powered by a novel peptide.

A Look That Lasts

Keep your frown lines smoother for a full year with as few as 2 treatments.*

High Satisfaction

96% of people were satisfied with their results.†

*Conventional frown line treatments last 3-4 months. At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment with DAXXIFY. In other safety studies, between 5% and 17% of patients still had noticeable improvement 9 months later.

†96% of patients reported they were satisfied on a 7-point scale when evaluated at 4 weeks in clinical studies.

Long-lasting frown line treatment

We are proud to offer the latest in advanced cosmetic treatments.

Introducing DAXXIFY, the FDA-approved, long-lasting frown line treatment powered by a unique peptide. If you've been seeking a solution to smooth those moderate to severe lines between your brows, DAXXIFY might be just what you need.

Let us tell you more about this innovative product.

Long-lasting frown line treatment

Frequently Asked Questions

The active ingredient in DAXXIFY is a purified protein called botulinum toxin type A. DAXXIFY is FDA-approved to smooth moderate to severe lines between the brows. It is the only long-lasting frown line treatment powered by a peptide with results that last on average 6 months and up to 9 months for some.

Is your frown line treatment not lasting as long as you would like? If so, DAXXIFY could be the solution for you. Contact Greenwich Dermatology to discuss your treatment goals.

All frown line treatments require a special ingredient to stabilize botulinum toxin A, the protein responsible for helping smooth moderate to severe frown lines. For instance, BOTOX Cosmetic uses human serum albumin (HSA), a blood product, as its stabilizer. Dysport, another frown line treatment, uses HSA as a stabilizer and cow’s milk protein as a protectant. DAXXIFY is unique because it is the only formulation that uses a novel peptide as a stabilizer and does not contain human or animal byproducts.

Probably not. Units are like fingerprints—they are a proprietary measurement of a treatment’s unique potency. Because of the differences in how treatments are formulated and tested, you cannot compare or convert Units between them, just like you cannot compare 2 fingerprints.

DAXXIFY is manufactured in California. It is the only prescription frown line treatment made in the United States.

In 2002, physicians and entrepreneurs founded a start-up in Silicon Valley, California to explore the use of peptides in biologics for different therapeutic uses. Their goal was to utilize peptides to transport biologics, typically large molecules, through the skin. Several clinical studies were created to determine the correct dose for an injectable product that would treat frown lines. In clinical studies, DAXXIFY lasted on average 6 months and up to 9 months for some people.

DAXXIFY was studied in the largest-ever clinical study for a frown line treatment and included more than 2,800 people across different ages and skin types. The active ingredient in DAXXIFY is botulinum toxin type A, an ingredient that has been used in frown line treatments for more than 20 years. 96% of people treated with DAXXIFY were satisfied with their results. There were no serious treatment-related side effects, but you should talk with our doctors about possible side effects and consult with the Prescribing Information and Medication Guide.

The safety and efficacy of DAXXIFY is well established, with more than 20 years of research. In fact, DAXXIFY has been studied in the largest-ever phase 3 clinical trial conducted for a frown line treatment and included more than 2,800 people across different ages and with different skin types. DAXXIFY was studied in patients with varying skin types.

No, not necessarily. The most common side effects observed in clinical trials occurred within one to two weeks after injection and lasted only a short while. This is consistent with other frown line treatments. DAXXIFY is well-studied, with no serious treatment-related side effects seen in large-scale clinical trials.

Talk to us for pre-treatment instructions prior to your DAXXIFY appointment. A list of common avoidances before treatment include, but are not limited to:

  • Retin-A
  • Blood thinners
  • Muscle relaxants
  • Fish or oils rich in omega 3
  • Allergy medication
  • Topical steroids
  • Sleep medications and supplements
  • Aspirin
  • St. John’s Wort
  • Supplements containing Vitamin E
  • Ibuprofen

DAXXIFY injections are typically performed with a small needle and people treated with frown line treatments say the injection feels like a pinch.If you are concerned about discomfort, talk to us about options for minimizing pain, such as icing the area or applying a topical numbing cream. Treatment with DAXXIFY requires minimal downtime, and you can return to your daily routine immediately after your appointment. There is a possibility that the area around the injection site will swell, turn red, and cause pain or tenderness from the injection itself. However, these side effects are typically very minor and go away after a few hours or days.

If you’re like most people, you probably get a frown line treatment around twice a year. But here’s the thing: conventional treatments only last 3–4 months. If you are not able to get treated every 3-4 months, that means you may spend the next 2-3 months of the year with those frown lines staring back at you between treatments. That’s up to 4-6 months of total wear off time per year! DAXXIFY is different. With those same 2 treatment visits, you can keep your frown lines smoother for a full year!

You may see results with DAXXIFY as early as the next day after treatment, and typically within two days.

You may see results with DAXXIFY as early as the next day after treatment, and typically within two days. You should see noticeable results within a two-week time frame. You may experience mild injection-related bruising. In most cases, bruising heals within a few days after injection.

Several factors contribute to the formation of facial lines. Decreased collagen production, cellular changes, genetics, environmental damage, and sun damage may all play a role. Facial lines are also formed by repeated muscle contractions such as frowning, squinting, or raising the eyebrows. These facial expressions cause the skin to furrow and fold, which eventually leads to the formation of wrinkles. DAXXIFY works below the skin's surface to temporarily reduce the underlying muscle activity responsible for moderate to severe frown lines.

Botulinum toxins are biologics, produced from a bacterium called Clostridium botulinum. They are used to inhibit the transmission of specific chemical signals from nerves, primarily those signals that cause muscular contractions. Botulinum toxin type A injections temporarily relax the facial muscles that cause wrinkles between the brows, reducing their appearance. Injections of specific botulinum toxin formulations are also utilized in the treatment of medical conditions.

Injectable wrinkle treatments containing botulinum toxin type A have been used to improve the look of moderate to severe frown lines for more than 20 years. The first FDA-approved treatment was BOTOX Cosmetic, followed by Dysport, Xeomin, and Jeuveau. Although today’s wrinkle reducers all contain botulinum toxin type A, it’s important to know that no 2 treatments are alike and cannot be interchanged with each other.

DAXXIFY minimizes the appearance of moderate to severe frown lines by temporarily relaxing the underlying muscles that cause these wrinkles. It is a long-lasting botulinum type A treatment with a novel peptide. Facial fillers, also known as dermal fillers, are typically made of hyaluronic acid and are used to add volume, fullness, and structure to areas of the face. They can help contour cheekbones, soften lines around the nose and mouth, and volumize lips. Dermal fillers target volume loss rather than muscle-related wrinkles.

Experience the innovation

Experience the innovation

DAXXIFY is not only a groundbreaking frown line treatment; it is also the only prescription product of its kind made in the United States. Developed in Silicon Valley, DAXXIFY continues to be manufactured there, representing the cutting edge of cosmetic innovation.

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Safety Information

Please be aware of the important safety information associated with DAXXIFY. It may cause serious side effects that can be life-threatening. If you experience any problems swallowing, speaking, or breathing due to weakening of associated muscles, seek medical help immediately, especially if these problems are pre-existing before injection. Additionally, be cautious of the potential spread of toxin effects, which may affect areas away from the injection site and cause serious symptoms.

For your safety, do not receive DAXXIFY if you are allergic to any of its ingredients or have had an allergic reaction to other botulinum toxin products. If you have any medical conditions or are taking certain medications, consult your healthcare provider before receiving DAXXIFY. For a comprehensive list of possible side effects and more detailed safety information, please refer to the full Prescribing Information and Medication Guide.

Discover the power of DAXXIFY today and book your consultation at Greenwich Dermatology. Let our experienced team help you achieve a smoother, more youthful appearance that lasts.